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Monday, 20 May 2013

Tapas Time - Statins Part 4

Today’s post is bite-sized, as opposed to the occasional shock to the digestive system that I serve up.

You may have been wondering how come a few American researchers have managed to keep a lid on the neuroprotective power of statins; or even that Peter and Monty are making it all up.

Well, for a change from the usual Anglo-Saxon research, today I present you a paper from Granada in Spain.
 
Statins as neuroprotectants: acomparative in vitro study of lipophilicity, blood-brain-barrier penetration,lowering of brain cholesterol, and decrease of neuron cell death.

They study which statin should be the most neuroprotective.  Their choice is Simvastatin, which is also known as Zocor.  In the UK, Zocor is now an over the counter (OTC) drug, meaning no prescription required.


The previous posts on Statins are here:-

Statins Part 1
Statins Part 2
Statins Part 3


 


 

4 comments:

  1. Hi Peter,

    I trialed atorvastatin(lipitor) a few weeks back, small 5mg tablet but very bitter, when crushed it even changed the flavor of the juice so it was very difficult to dose. I gave 5mg and went to the office, I called mom to ask what the report was she said nothing much just the usual (kept her blind) when I came home from the office he cried like small burst of crying for like 5 seconds then would stop (like trying to tell me something) he never does that though. Perhaps I should try for 2-3 days.

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    Replies
    1. Salh, best to try again at the weekend when you can observe changes. Small changes can be important or just a random coincidence.

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  2. Meenakshi Ramesh11 July 2024 at 06:57

    Hi Peter
    I started Atorvastatin for my 23 year old son just a couple of days back. I gave him 20 mg and I’m already seeing subtle improvements in his cognition.

    My son has severe acid reflux issues. I’m wondering if statins can make his reflux issues worse.

    Please share your thoughts.

    Thank you 🙏 so much for this blog. I received your book as a gift from a friend.

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    Replies
    1. Hi Meenakski, there is a rare issue with statins triggering reflux in some people, so it certainly is possible. I suggest you lower your dose to 10mg, the effect on reflux would likely be dose dependent.

      If you are not already doing it, raise the head end of your son's bed by about 15cm. This stops acid rising up the esophagus when he is lying down. It is a trick known for decades, but not everyone knows about it these days.

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