The three autism
comorbidities that I have chosen to investigate are asthma, high cholesterol
and various types of seizure.
You can check use of my autism drugs in each comorbidity using Google, or just look at the links I selected below.
Do statins improve outcomesin patients with asthma on inhaled corticosteroid therapy?
High Cholesterol (cardiac
treatment)
(then click for full version)
Can Statins Lower the Risk for Epilepsy?
Phase 1
The first
phase is the easy one. I just need to
see if my autism drugs are proven to be effective in the each comorbidity. The results really surprised me.
With the exception
of bumetanide and asthma, there is a perfect overlap. Even more surprising, is that another loop
diuretic, called furosemide, which is very similar to bumetanide, has been
showed to be effective in asthma when given in the inhaled form.
In the case
of cholesterol, I am looking at elevated levels in cardiology. The use of bumetanide in people with heart
problems associated with high cholesterol is to reduce blood pressure
(anti-hypertensive).
NAC improves
effectiveness of the conventional corticosteroid therapy, particularly in hard
to treat cases like current or past smokers. In COPD a severe form of asthma,
read: The role for N-acetylcysteine in the management of COPD
Do statins improve outcomesin patients with asthma on inhaled corticosteroid therapy?
NAC raises
your good HDL cholesterol level, so lowering your overall cholesterol risk
factor.
Statins were
primarily developed to lower cholesterol as part of cardiac treatment.
Bumetanide
is a loop diuretic and anti-hypertensive drug primarily marketed as a cardiac
drug.
Seizures
(then click for full version)
Can Statins Lower the Risk for Epilepsy?
Phase 2
The second
phase involves understanding each comorbidity and seeing if any of their
established treatments can be effective in treating autism.
This will also produce some surprises in the following posts.
This will also produce some surprises in the following posts.